It sounds like you’re trying to animate a shader,.. you do that by moving the time-line forward ad adjusting a value in any part of the shader,. which creates a Key-frame. (see pics)
You can then duplicate that key-frame or add more..
Back in the assembly room you can select different “Tweener” types, to effect the way the values transition from one key to the next
Frame 0 = red glow
Frame 30 = Black (no glow)
Using an Oscillate tweener, you can get it to pulse between the two key-frames
EDIT: I think I’ve misread this,.. the issue is that the colour wheel isn’t changing anything, if you save a colour wheel value, then move the time-line and load one of the saved value, ...
It’‘s working ok for me here.
What may be throwing you is that the Little Colour wheel panel can remain open. although you’ve clicked somewhere else, and any change you make doesn’t apply to anything,
You need to select the little colour Box, to bring up the colour wheel for that colour again.
Hope it helps