Yes, absolutely. I’ve had items printed by Shapeways with no problems but you have to make sure you follow all the requirements for digital printing just like you would from any application or for any 3D printer. Hexagon is fine for doing this and I’ve had excellent results.
Once you have your mesh use the free version of “Netfabb” to check and correct any problems.
I find holes in the mesh and getting the scale right are the main things that can cause problems but I’ve always been able to sort them out before getting things printed and haven’t had any failures.