I’m not the best person, but I can try to help when it comes to Luxrender settings.
as for lights, I suggest setting up some primatives with a large panel aimed at the characters or scene and rename them or convert them to lights when you import your scene to Reality.
Once in Luxrender you can adjust the settings such as brightness and color as it renders.
Take the Starship Bridge 8 for example. (ie TNG bridge) Convert the dome texture to a light in Reality and then when you render adjust as needed for color and brightness.
Most of Rduda’s sets have perfect placement of lights. Just remember to convert the textures to lights (thumping foot on floor to share the point.)
Good luck. As for skin settings I made some pointers in the body of the comments to Mylochka’s Uhura image over at DA. Lux will do SSS settings it just takes a bit of figureing out.
These will work for both the DAZ and Poser versions, I’ve read over the manuals enough times to have a fair understanding of each.
(Manuals…gotta love them! they actually make life easier and understandable! Thumping foot on floor to share the point again! Nuff said.)