I’ve tried it out on genesis, and they mostly work. As I recall, you can’t use the eyebrow options without workarounds. Also you would have to transfer the eye morphs with GenX if you wanted to use those. Textures worked fine though.
There may be something I’m forgetting. I thought they were neat, but I ended up returning them because it was just enough trouble getting them fully working with genesis that I thought it would be unlikely I would use them that often.
Edit: better info from SnowSultan (and others) while I was typing. Yes the eye surface shadow thing was what I was forgetting, I thought there was something else I ran into. Thought they were very cool though.