While you could use AutoFit to convert the skeleton to Genesis I’m not sure how good the results would be - you’d lose the rigging by bone, it would just be rigged by the Genesis body parts so there’d be more distortion as it was posed, and the body handles would be merged with the reset of the mesh (though they could still be hidden through their materials you couldn’t stop dynamic cloth from colliding with them). That’s assuming you are wanting the skeleton embedded in a human - if not you should be able to use the V4/M4 skeletons as stand alone figures just fine.